We all accept that getting older is inevitable, and now leading clinicians have revealed the exact age when different body parts start to decline, most alarming being the brain and lungs.
French doctors have found that the quality of men's' sperm starts to deteriorate by 35, so that by the time a man is 45 a third of pregnancies end in miscarriage. Here, with the help of leading clinicians, Angela Epstein tells the Daily Mail the ages when different parts of the body start to lose their battle with time.
BRAIN - Starts ageing at 20. As we get older, the number of nerve cells - or neurons - in the brain decrease. We start with around 100 billion, but in our 20s this number starts to decline. By 40, we could be losing up to 10,000 per day, affecting memory, co-ordination and brain function.
GUT - Starts ageing at 55. A healthy gut has a good balance betwee harmful and 'friendly' bacteria. But levels of friendly bacteria in the gut drop significantly after 55, particularly in the large intestine, says Tom MacDonald, professor of immunology at Barts And The London medical school. As a result, we suffer from poor digestion and an increased risk of gut disease. Constipation is more likely as we age, as the flow of digestive juices from the stomach, liver, pancreas and small intestine slows down.
HEART - Starts ageing at 40. The heart pumps blood less effectively around the body as we get older. This is because blood vessels become less elastic, while arteries can harden or become blocked because of fatty deposits forming on the coronary arteries - caused by eating too much saturated fat. The blood supply to the heart is then reduced, resulting in painful angina. Men over 45 and women over 55 are at greater risk of a heart attack.
LIVER - Starts ageing at 70. This is the only organ in the body which seems to defy the aging process.
KIDNEYS - Starts ageing at 50. With kidneys, the number of filtering units (nephrons) that remove waste from the bloodstream starts to reduce in middle age.
PROSTATE - Starts ageing at 50. The prostate often becomes enlarged with age, leading to problems such as increased need to urinate, says Professor Roger Kirby, director of the Prostate Centre in London . This is known as benign prostatic hyperplasia and affects half of men over 50, but rarely those under 40. It occurs when the prostate absorbs large amounts of the male sex hormone testosterone, which increases the growth of cells in the prostate. A normal prostate is the size of a walnut, but the condition can increase this to the size of a tangerine.
BONES - Start ageing at 35. Throughout our life, old bone is broken down by cells called osteoclasts and replaced by bone-building cells called osteoblasts - a process called bone turnover,' explains Robert Moots, professor of rheumatology at Aintree University Hospital in Liverpool . Children's bone growth is rapid - the skeleton takes just two years to renewitself completely. In adults, this can take ten years. Until our mid-20s, bone density is still increasing. But at 35 bone loss begins as part of the natural ageing process.
TEETH - Start ageing at 40. As we age, we produce less saliva, which washes away bacteria, so teeth and gums are more vulnerable to decay. Receding gums - when tissue is lost from gums around the teeth - is common in adults over 40.
MUSCLES - Start ageing at 30. Muscle is constantly being built up and broken down, a process which is well balanced in young adults. However, by the time we're 30, breakdown is greater than buildup, explains Professor Robert Moots. Once adults reach 40, they start to lose between 0.5 and 2 per cent of their muscle each year. Regular exercise can help prevent this.
HEARING - Starts ageing mid-50s. More than half of people over 60 lose hearing because of their age, according to the Royal National Institute for the Deaf.
SKIN - Starts ageing mid-20s. The skin starts to age naturally in your mid-20s.
TASTE AND SMELL - Start ageing at 60. We start out in life with about 10,000 taste buds scattered on the tongue. This number can halve later in life. After we turn 60, taste and smell gradually decline, partly as a result of the normal ageing process.
FERTILITY - Starts ageing at 35. Female fertility begins to decline after 35, as the number and quality of eggs in the ovaries start to fall. The lining of the womb may become thinner, making it less likely for a fertilised egg to take, and also creating an environment hostile to sperm.
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